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the binder from a solid to a liquid or molten state and it then act s as the granulating liquid. Once the granulation process has been completed, the system is cooled, the binder reverts. to a ...
Wet Granulation Process : Pharmaceutical Guidelines
Wet granulation involves the massing of a mix of dry primary powder particles using a granulating fluid.The fluid contains a solvent which can be removed by drying, and should be non-toxic.Typical solvents include water, ethanol and isopropanol and methylene chloride either alone or in combination. The granulation liquid may be used alone or, more usually, as a solvent …
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